Release 56
(Apr 24, 2025)

QTL 160243 Description:

 Trait Information
Trait name: Hair density Vertebrate Trait Ontology: Hair amount
Reported name: hypotrichosis Product Trait Ontology: n/a
Symbol: HSPARS Clinical Measurement Ontology: n/a
 QTL Map Information
Chromosome:11
QTL Peak Location:n/a
QTL Span:n/a
48.2-48.4 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:rs396830038
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:Association
Model tested:Mendelian
Test base:Genome-wise
Threshold significance level:Significant
P_values0.02268
Dominance effect:n/a
Additive effect:n/a
Associated Gene:n/a
Cis/Trans acting type:
Links:   Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Curly-coated horses included American Bashkir Curly, Miniature ABC, Kentucky Mountain Saddle Horse, Foxtrotter, Oldenburger, Danish Warmblood, Holsteiner, and ABCH/QH crossbreed. Straight-coated horses comprised ABCHs, QH, Missouri Foxtrotter, Oldenburger, and ABCH/Paint horse cross.
     Breeds associated:
    Design:Animals were genotyped using the Affymetrix Axiom Equine Genotyping Array 670K and analyzed for curly vs. straight coat and presence of hypotrichosis. A total of
    Analysis:A max (T) permutation test was done. Following GWAS, next-generation sequencing was performed to identify possible causative variants for curly coat and hypotrichosis.
    Software:PLINK, SAS, Beagle
    Notes: 
    Links:Edit

     Reference
    Authors:Thomer A, Gottschalk M, Christmann A, Naccache F, Jung K, Hewicker-Trautwein M, Distl O, Metzger J
    Affiliation:Institute for Animal Breeding and Genetics, University of Veterinary Medicine Hannover Foundation, Hannover, 30559, Germany
    Title:An epistatic effect of KRT25 on SP6 is involved in curly coat in horses
    Journal:Scientific reports, 2018, 8(1): 6374
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #29686323
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  • Cite this Data:

    Animal QTLdb: QTL160243 was published in 2018, and was curated into QTLdb on 2018-07-18. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:160243

     

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