QTL Map Information |
Chromosome: | 11 |
QTL Peak Location: | n/a |
QTL Span: | n/a 48.2-48.4 (Mbp) |
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Upper, "Suggestive": | n/a |
Upper, "Significant": | n/a |
Peak: | rs68807441 |
Lower, "Significant": | n/a |
Lower, "Suggestive": | n/a |
Marker type: | SNP |
Analysis type: | Association |
Model tested: | Mendelian |
Test base: | Genome-wise |
Threshold significance level: | Significant |
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P_values | 0.01429 | Dominance effect: | n/a |
Additive effect: | n/a |
Associated Gene: | n/a |
Cis/Trans acting type: |  |
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Extended information: |
(none) |
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QTL Experiment in Brief |
Animals: | Curly-coated horses included American Bashkir Curly, Miniature ABC, Kentucky Mountain Saddle Horse, Foxtrotter, Oldenburger, Danish Warmblood, Holsteiner, and ABCH/QH crossbreed. Straight-coated horses comprised ABCHs, QH, Missouri Foxtrotter, Oldenburger, and ABCH/Paint horse cross. |
Breeds associated:
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Design: | Animals were genotyped using the Affymetrix Axiom Equine Genotyping Array 670K and analyzed for curly vs. straight coat and presence of hypotrichosis. A total of |
Analysis: | A max (T) permutation test was done. Following GWAS, next-generation sequencing was performed to identify possible causative variants for curly coat and hypotrichosis. |
Software: | PLINK, SAS, Beagle |
Notes: | |
Links: | Edit |
Reference |
Authors: | Thomer A, Gottschalk M, Christmann A, Naccache F, Jung K, Hewicker-Trautwein M, Distl O, Metzger J |
Affiliation: | Institute for Animal Breeding and Genetics, University of Veterinary Medicine Hannover Foundation, Hannover, 30559, Germany |
Title: | An epistatic effect of KRT25 on SP6 is involved in curly coat in horses |
Journal: | Scientific reports, 2018, 8(1): 6374 |
Links: |
PubMed | Abstract | List all data
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