Release 56
(Apr 24, 2025)

QTL 23181 Description:

 Trait Information
Trait name: Milk vitamin B-12 content Vertebrate Trait Ontology: n/a
Reported name: Milk vitamin B-12 content Product Trait Ontology: Milk vitamin B-12 content
Symbol: MVB12 Clinical Measurement Ontology: n/a
 QTL Map Information
Chromosome:4
QTL Peak Location:112.18 (cM)
QTL Span:112.18-112.18 (cM)
113.6-113.6 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:rs17871621
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:Association
Model tested:Mendelian
Test base:Comparison-wise
Threshold significance level:Significant
P_values9.55E-4
Dominance effect:0.09
Additive effect:0.52
Associated Gene:SLC4A2 (solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1))
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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    •  QTL Experiment in Brief
    Animals:Animals were Dutch Holstein Friesian cows.
     Breeds associated:
    Design:Animals were genotyped using the 50K Infinium SNP chip and analyzed for milk vitamin B-12 content. The final marker set included 49994 markers.
    Analysis:An animal model was used.
    Software:ASReml
    Notes:A number of significant data points were not entered due to lack of SNP ID.
    Links:Edit

     Reference
    Authors:Rutten Marc J M, Bouwman Aniek C, Sprong R Corinne, van Arendonk Johan A M, Visker Marleen H P W
    Affiliation:Animal Breeding and Genomics Centre, Wageningen University, Wageningen, The Netherlands
    Title:Genetic variation in vitamin B-12 content of bovine milk and its association with SNP along the bovine genome
    Journal:PloS one, 2013, 8 (4): e62382
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #23626813
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    • Cite this Data:

    Animal QTLdb: QTL23181 was published in 2013, and was curated into QTLdb on 2013-12-31. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:23181

     

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