| QTL Map Information |
|---|
| Chromosome: | 22 |
| QTL Peak Location: | 77.69 (cM) |
| QTL Span: | 77.69-77.69 (cM)
51.3-51.3 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | rs876174537 |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | Association |
| Model tested: | Mendelian |
| Test base: | Genome-wise |
| Threshold significance level: | Significant |
 |
P_values | <0.05 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | COL7A1 (collagen type VII alpha 1 chain) |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
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| QTL Experiment in Brief |
|---|
| Animals: | Animals were Vorderwald cattle. |
| Breeds associated:
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| Design: | Animals were genotyped using the Illumina BovineSNP50 BeadChip and analyzed for haplotype association with epidermolysis bullosa incidence. A total of 41,436 SNPs were used for analysis. |
| Analysis: | A linear regression model was used. |
| Software: | GCTA, SAMtools, Beagle, R software, PLINK, FINDHAP |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Pausch H, Ammermüller S, Wurmser C, Hamann H, Tetens J, Drögemüller C, Fries R |
| Affiliation: | Chair of Animal Breeding, Technical University of Munich, Freising, 85354, Germany |
| Title: | A nonsense mutation in the COL7A1 gene causes epidermolysis bullosa in Vorderwald cattle |
| Journal: | BMC genetics, 2016, 17(1): 149 |
| Links: |
PubMed | Abstract | List all data
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