QTLdb: entrichment tests

Release 56
(Apr 24, 2025)

Whole genome analysis for QTL/association enrichment

Running...

Version: Enrich S: beta v0.8

Search:	to limit the list of your trait choices:
	(optional) focus on chromosome with Mb windows across its length

Data:

Number of chemistry traits:	33
Number of QTL / associations found:	849
Number of chromosomes where QTL / associations are found:	30

Chi-squared (χ²) test: are chemistry traits over-represented on some chromosomes?

Chromosomes	Total χ²	df	p-values	FDR ^*	Size of χ²
Chromosome X	3.36996	29	0.998329325823115	9.999246e-01
Chromosome 1	0.10494	29	0.998329325823115	9.999246e-01
Chromosome 2	452.54319	29	1.520971e-77	9.125826e-77
Chromosome 3	325.20741	29	8.059047e-52	2.686349e-51
Chromosome 4	12.69873	29	0.9962364	9.999246e-01
Chromosome 5	100.85394	29	7.139162e-10	9.735221e-10
Chromosome 6	452.54319	29	1.520971e-77	9.125826e-77
Chromosome 7	1171.77984	29	3.659281e-228	1.097784e-226
Chromosome 8	325.20741	29	8.059047e-52	2.686349e-51
Chromosome 9	3489.00948	29	9e-41	1.800000e-40
Chromosome 10	287.42637	29	2.462608e-44	7.387824e-44
Chromosome 11	21.56088	29	0.8379096	9.668188e-01
Chromosome 12	148.89633	29	4.565741e-18	6.848612e-18
Chromosome 13	176.41602	29	4.610648e-23	7.279971e-23
Chromosome 14	21.56088	29	0.8379096	9.668188e-01
Chromosome 15	8.50080	29	0.9999246	9.999246e-01
Chromosome 16	206.26749	29	1.222489e-28	2.037482e-28
Chromosome 17	272.96709	29	1.701840e-41	3.927323e-41
Chromosome 18	123.70908	29	1.152176e-13	1.645966e-13
Chromosome 19	206.26749	29	1.222489e-28	2.037482e-28
Chromosome 20	46.28151	29	0.02199616	2.749520e-02
Chromosome 21	272.96709	29	1.701840e-41	3.927323e-41
Chromosome 22	2435.34159	29	9e-41	1.800000e-40
Chromosome 23	434.35227	29	7.813235e-74	3.906618e-73
Chromosome 24	529.03785	29	3.042616e-93	3.042616e-92
Chromosome 25	390.50781	29	6.206916e-65	2.660107e-64
Chromosome 26	52.34526	29	0.004987569	6.505525e-03
Chromosome 27	238.45140	29	8.712407e-35	1.633576e-34
Chromosome 28	688.55721	29	2.420131e-126	3.630197e-125
Chromosome 29	272.96709	29	1.701840e-41	3.927323e-41

Chi-squared (χ²) test: Which of the 33 chemistry traits are over-represented in the QTLdb

Traits	Total χ²	df	p-values	FDR ^*	Size of χ²
Calpain activity	101.95949	32	3.169022e-09	1.742962e-08
Hematin pigment concentration	16.68749	32	0.9881668	9.881668e-01
Insoluble collagen content	16.68749	32	0.9881668	9.881668e-01
Muscle anserine content	317.59914	32	9.402531e-49	3.102835e-47
Muscle arsenic content	83.89999	32	1.548711e-06	4.258955e-06
Muscle beta-alanine content	87.90125	32	4.118552e-07	1.235566e-06
Muscle calcium content	66.90079	32	0.0002914481	6.411858e-04
Muscle carnosine content	173.75063	32	2.082447e-21	2.290692e-20
Muscle chromium content	22.4099	32	0.8960537	9.881668e-01
Muscle cobalt content	16.68749	32	0.9881668	9.881668e-01
Muscle copper content	46.16666	32	0.05027979	8.732806e-02
Muscle creatine content	119.77635	32	4.536011e-12	3.742209e-11
Muscle creatinine content	57.06741	32	0.004152643	8.564826e-03
Muscle glucose 6-phosphatase activity	29.32142	32	0.6028001	8.648871e-01
Muscle glycogen content	93.33332	32	6.516261e-08	2.389296e-07
Muscle iron content	75.9796	32	1.936889e-05	4.916718e-05
Muscle lactate dehydrogenase activity	22.00445	32	0.9072773	9.881668e-01
Muscle magnesium content	26.99203	32	0.7181694	9.874829e-01
Muscle manganese content	16.68749	32	0.9881668	9.881668e-01
Muscle moisture content	20.14377	32	0.9487188	9.881668e-01
Muscle nitrogen content	18.29544	32	0.97495	9.881668e-01
Muscle pH	95.51861	32	3.061438e-08	1.262843e-07
Muscle phosphorus content	32.52895	32	0.4407376	6.925877e-01
Muscle potassium content	52.02207	32	0.01409749	2.736572e-02
Muscle protein percentage	104.87691	32	1.113093e-09	7.346414e-09
Muscle protein/DNA ratio	17.86666	32	0.9792312	9.881668e-01
Muscle selenium content	40.65808	32	0.1402095	2.313457e-01
Muscle sodium content	50.90672	32	0.01819513	3.335774e-02
Muscle sulfur content	29.32142	32	0.6028001	8.648871e-01
Muscle taurine content	272.29729	32	6.536633e-40	1.078544e-38
Muscle total collagen content	101.41168	32	3.852089e-09	1.815985e-08
Muscle zinc content	74.82168	32	2.76945e-05	6.527989e-05
beta-carotene concentration in fat	90.61557	32	1.649471e-07	5.443254e-07

Correlations found between some of these traits for your reference

No correlation data found on these traits

Overall Test

Data		Chi'Square Test			Fisher's Exact Test
Number of chrom.:	30	χ²	=	13167.699600
Number of traits:	33	df	=	928
Number of QTLs:	849	p-value	=	0

FOOT NOTE: * : FDR is short for "false discovery rate", representing the expected proportion of type I errors. A type I error is where you incorrectly reject the null hypothesis, i.e. you get a false positive. It's statistical definition is FDR = E(V/R | R > 0) P(R > 0), where V = Number of Type I errors (false positives); R = Number of rejected hypotheses. Benjamini–Hochberg procedure is a practical way to estimate FDR.