QTLdb: entrichment tests

Release 57
(Aug 26, 2025)

Whole genome analysis for QTL/association enrichment

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Version: Enrich S: beta v0.8

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Data:

Number of milk composition - protein traits:	36
Number of QTL / associations found:	26,307
Number of chromosomes where QTL / associations are found:	30

Chi-squared (χ²) test: are milk composition - protein traits over-represented on some chromosomes?

Chromosomes	Total χ²	df	p-values	FDR ^*	Size of χ²
Chromosome X	22051.68984	29	9e-41	9.642857e-41
Chromosome 1	268.68888	29	1.169630e-40	1.209962e-40
Chromosome 2	3057.45084	29	9e-41	9.642857e-41
Chromosome 3	1010.64420	29	4.873499e-194	1.462050e-192
Chromosome 4	19033.51932	29	9e-41	9.642857e-41
Chromosome 5	17.93268	29	0.9456326	9.456326e-01
Chromosome 6	2128874.76756	29	9e-41	9.642857e-41
Chromosome 7	7481.77668	29	9e-41	9.642857e-41
Chromosome 8	14529.15540	29	9e-41	9.642857e-41
Chromosome 9	14873.08680	29	9e-41	9.642857e-41
Chromosome 10	7169.63724	29	9e-41	9.642857e-41
Chromosome 11	42053.22252	29	9e-41	9.642857e-41
Chromosome 12	18423.51048	29	9e-41	9.642857e-41
Chromosome 13	4019.42160	29	9e-41	9.642857e-41
Chromosome 14	329515.79652	29	9e-41	9.642857e-41
Chromosome 15	3866.75100	29	9e-41	9.642857e-41
Chromosome 16	3891.99096	29	9e-41	9.642857e-41
Chromosome 17	14044.80384	29	9e-41	9.642857e-41
Chromosome 18	16862.92740	29	9e-41	9.642857e-41
Chromosome 19	9533.80548	29	9e-41	9.642857e-41
Chromosome 20	90788.90508	29	9e-41	9.642857e-41
Chromosome 21	17931.80196	29	9e-41	9.642857e-41
Chromosome 22	15826.89600	29	9e-41	9.642857e-41
Chromosome 23	3717.03636	29	9e-41	9.642857e-41
Chromosome 24	17823.43656	29	9e-41	9.642857e-41
Chromosome 25	17339.85684	29	9e-41	9.642857e-41
Chromosome 26	13853.36196	29	9e-41	9.642857e-41
Chromosome 27	26465.21028	29	9e-41	9.642857e-41
Chromosome 28	23148.16884	29	9e-41	9.642857e-41
Chromosome 29	1895.94288	29	9e-41	9.642857e-41

Chi-squared (χ²) test: Which of the 36 milk composition - protein traits are over-represented in the QTLdb

Traits	Total χ²	df	p-values	FDR ^*	Size of χ²
Milk alpha-S1-casein content	65.60002	35	0.001307177	2.352919e-03
Milk alpha-S1-casein percentage	155.44962	35	4.054393e-17	8.585773e-17
Milk alpha-S2-casein percentage	228.30787	35	3.210643e-30	8.891011e-30
Milk alpha-casein content	40.21587	35	0.2502394	3.106420e-01
Milk alpha-casein percentage	42.19056	35	0.1880045	2.417201e-01
Milk alpha-casein to beta-casein ratio	4.51325	35	1	1.000000e+00
Milk alpha-lactalbumin content	8.50863	35	0.9999988	1.000000e+00
Milk alpha-lactalbumin percentage	183.84416	35	4.238636e-22	9.536931e-22
Milk beta-casein content	12.58874	35	0.9998231	1.000000e+00
Milk beta-casein percentage	476.73302	35	6.333512e-79	1.140032e-77
Milk beta-lactoglobulin percentage	2290.30169	35	9e-41	2.700000e-40
Milk beta-lactoglobulin protein content	2378.46056	35	9e-41	2.700000e-40
Milk casein content	60.26344	35	0.005013737	7.520605e-03
Milk casein index	154.72223	35	5.405005e-17	1.081001e-16
Milk casein percentage	828.00255	35	2.931064e-151	1.055183e-149
Milk casein yield	63.17179	35	0.002440438	3.993444e-03
Milk delta-9-desaturase content	288.06389	35	1.520714e-41	1.368643e-40
Milk glycosylated kappa-casein percentage	2004.62179	35	9e-41	2.700000e-40
Milk immunoglobulin G content	35.53752	35	0.4429052	5.314862e-01
Milk kappa-casein content	48.02171	35	0.07019116	9.358821e-02
Milk kappa-casein percentage	2826.84867	35	9e-41	2.700000e-40
Milk lactoferrin content	2238.75781	35	9e-41	2.700000e-40
Milk lactoperoxidase content	54.9685	35	0.01707120	2.458253e-02
Milk osteopontin content	4.51325	35	1	1.000000e+00
Milk phosphorylated alpha-S2-casein percentage	447.06065	35	6.117171e-73	7.340605e-72
Milk protein content	61.45201	35	0.003749888	5.869390e-03
Milk protein percentage	5459.91985	35	9e-41	2.700000e-40
Milk protein yield	2366.51941	35	9e-41	2.700000e-40
Milk protein yield persistency	50.00944	35	0.04800866	6.647353e-02
Milk protein-to-fat ratio	78.60456	35	3.395867e-05	6.434274e-05
Milk unglycosylated kappa-casein percentage	2096.60583	35	9e-41	2.700000e-40
Milk urea nitrogen content	201.11165	35	3.258983e-25	8.380242e-25
Milk urea nitrogen yield	199.07181	35	7.652884e-25	1.836692e-24
Milk whey protein content	64.63209	35	0.001680611	2.881047e-03
Milk whey protein percentage	22.21436	35	0.9540476	1.000000e+00
Milk whey protein yield	2.25664	35	1	1.000000e+00

Correlations found between some of these traits for your reference

No correlation data found on these traits

Overall Test

Data		Chi'Square Test			Fisher's Exact Test
Number of chrom.:	30	χ²	=	2889371.196000
Number of traits:	36	df	=	1015
Number of QTLs:	26,307	p-value	=	0

FOOT NOTE: * : FDR is short for "false discovery rate", representing the expected proportion of type I errors. A type I error is where you incorrectly reject the null hypothesis, i.e. you get a false positive. It's statistical definition is FDR = E(V/R | R > 0) P(R > 0), where V = Number of Type I errors (false positives); R = Number of rejected hypotheses. Benjamini–Hochberg procedure is a practical way to estimate FDR.